Template:PBB/5460

POU class 5 homeobox 1
識別記号
記号	POU5F1; OCT3; OCT4; OTF-3; OTF3; OTF4; Oct-3; Oct-4
その他ID	OMIM: 164177 MGI: 101893 HomoloGene: 8422 GeneCards: POU5F1 Gene
遺伝子オントロジー 分子機能 • sequence-specific DNA binding RNA polymerase II transcription factor activity • DNA binding • sequence-specific DNA binding transcription factor activity • protein binding • transcription factor binding • ubiquitin protein ligase binding • miRNA binding • sequence-specific DNA binding • transcription regulatory region DNA binding 細胞の構成要素 • nucleus • nucleoplasm • transcription factor complex • cytoplasm • cytosol 生物学的プロセス • endodermal cell fate specification • blastocyst development • BMP signaling pathway involved in heart induction • regulation of transcription, DNA-dependent • transcription from RNA polymerase II promoter • response to wounding • anatomical structure morphogenesis • regulation of asymmetric cell division • regulation of gene expression • somatic stem cell maintenance • positive regulation of catenin import into nucleus • mRNA transcription from RNA polymerase II promoter • positive regulation of transcription from RNA polymerase II promoter • positive regulation of SMAD protein import into nucleus • cell fate commitment involved in formation of primary germ layer • cardiac cell fate determination • negative regulation of gene silencing by miRNA • regulation of heart induction by regulation of canonical Wnt receptor signaling pathway • regulation of methylation-dependent chromatin silencing 出典: Amigo / EGO
RNA発現パターン
その他参照発現データ
オルソログ
種	ヒト	マウス
Entrez	5460	18999
Ensembl	ENSG00000204531	ENSMUSG00000024406
UniProt	Q01860	P20263
RefSeq (mRNA)	NM_001173531	NM_001252452
RefSeq (protein)	NP_001167002	NP_001239381
Location (UCSC)	Chr 6: 31.13 - 31.15 Mb	Chr 17: 35.51 - 35.51 Mb
PubMed search	[1]	[2]
KEGG GENES	hsa:5460	mmu:18999