Template:PBB/5879

Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
PDB rendering based on 1ds6.
PDBに登録されている構造 PDB Ortholog search: PDBe, RCSB, PDBj PDBのIDコード一覧 1FOE​, 1G4U​, 1I4D​, 1I4L​, 1I4T​, 1MH1​, 1RYF​, 1RYH​, 2FJU​, 2H7V​, 2NZ8​, 2P2L​, 2RMK​, 2VRW​, 2WKP​, 2WKQ​, 2WKR​, 2YIN​, 3B13​, 3BJI​, 3RYT​, 3SBD​, 3SBE​, 3SU8​, 3SUA​, 3TH5​, 4GZL​, 4GZM​
識別記号
記号	RAC1; Rac-1; TC-25; p21-Rac1
その他ID	OMIM: 602048 MGI: 97845 HomoloGene: 69035 ChEMBL: 6094 GeneCards: RAC1 Gene
遺伝子オントロジー 分子機能 • GTPase activity • protein binding • GTP binding • Rab GTPase binding • enzyme binding • protein kinase binding • GTP-dependent protein binding • thioesterase binding 細胞の構成要素 • Golgi membrane • phagocytic cup • trans-Golgi network • cytosol • plasma membrane • extrinsic to plasma membrane • lamellipodium • ruffle membrane • melanosome 生物学的プロセス • auditory receptor cell morphogenesis • mast cell chemotaxis • epithelial cell morphogenesis • apoptotic process • cellular component movement • inflammatory response • hyperosmotic response • cell adhesion • cell-matrix adhesion • small GTPase mediated signal transduction • axon guidance • blood coagulation • cell proliferation • response to wounding • anatomical structure morphogenesis • regulation of hydrogen peroxide metabolic process • positive regulation of lamellipodium assembly • viral reproduction • cerebral cortex radially oriented cell migration • embryonic olfactory bulb interneuron precursor migration • lamellipodium assembly • actin cytoskeleton organization • actin filament polymerization • platelet activation • regulation of cell migration • positive regulation of actin filament polymerization • T cell costimulation • ruffle organization • negative regulation of interleukin-23 production • substrate adhesion-dependent cell spreading • positive regulation of Rho protein signal transduction • intracellular signal transduction • Fc-gamma receptor signaling pathway involved in phagocytosis • positive regulation of phosphatidylinositol 3-kinase activity • engulfment of apoptotic cell • innate immune response • cell-cell junction organization • bone resorption • positive regulation of DNA replication • neurotrophin TRK receptor signaling pathway • negative regulation of receptor-mediated endocytosis • anatomical structure arrangement • dendrite morphogenesis • cell motility • regulation of defense response to virus by virus • localization within membrane • Wnt receptor signaling pathway, planar cell polarity pathway • regulation of respiratory burst • dopaminergic neuron differentiation • cochlea morphogenesis • ruffle assembly • apoptotic signaling pathway 出典: Amigo / EGO
RNA発現パターン
その他参照発現データ
オルソログ
種	ヒト	マウス
Entrez	5879	19353
Ensembl	ENSG00000136238	ENSMUSG00000001847
UniProt	P63000	P63001
RefSeq (mRNA)	NM_006908	NM_009007
RefSeq (protein)	NP_008839	NP_033033
Location (UCSC)	Chr 7: 6.41 - 6.44 Mb	Chr 5: 143.51 - 143.53 Mb
PubMed search	[1]	[2]
KEGG GENES	hsa:5879	mmu:19353